Publications of Jakub Chrustowicz

Gottemukkala, K. V.; Chrustowicz, J.; Sherpa, D.; Sepic, S.; Tung Vu, D.; Karayel, O.; Papadopoulou, E. C.; Gross, A.; Schorpp, K.; von Gronau, S. et al.; Hadian, K.; Murray, P. J.; Mann, M.; Schulman, B. A.; Alpi, A. F.: Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism. Molecular Cell 84 (10), pp. 1948 - 1963.e11 (2024)

Gross, A.; Müller, J.; Chrustowicz, J.; Strasser, A.; Gottemukkala, K. V.; Sherpa, D.; Schulman, B. A.; Murray, P. J.; Alpi, A. F.: Skraban-Deardorff intellectual disability syndrome-associated mutations in WDR26 impair CTLH E3 complex assembly. FEBS Letters 598 (9), pp. 978 - 994 (2024)

Chrustowicz, J.; Sherpa, D.; Li, J.; Langlois, C. R.; Papadopoulou, E. C.; Tung Vu, D.; Hehl, L. A.; Karayel, Ö.; Beier, V.; Gronau, S. v. et al.; Müller, J.; Prabu, J. R.; Mann, M.; Kleiger, G.; Alpi, A. F.; Schulman, B. A.: Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Molecular Cell 84 (2), pp. 293 - 308 (2024)

Sherpa, D.; Mueller, J.; Karayel, Ö.; Xu, P.; Yao, Y.; Chrustowicz, J.; Gottemukkala, K. V.; Baumann, C. A.; Gross, A.; Czarnecki, O. et al.; Zhang, W.; Gu, J.; Nilvebrant, J.; Sidhu, S. S.; Murray, P. J.; Mann, M.; Weiss, M. J.; Schulman, B. A.; Alpi, A. F.: Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11, e77937 (2022)

Langlois, C. R.; Beier, V.; Karayel, O.; Chrustowicz, J.; Sherpa, D.; Mann, M.; Schulman, B. A.: A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO Reports 23 (6), e53835 (2022)

Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)

Sherpa, D.; Chrustowicz, J.; Schulman, B.: How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini. Molecular Cell 82 (8), pp. 1424 - 1438 (2022)

Chrustowicz, J.: Mechanistic studies of GID/CTLH E3 ubiquitin ligases. Dissertation, TUM, Fakultät für Chemie, München (2022)